Vascularization strategies

The generation of thick, vascularized three-dimensional (3D) tissues is a key challenge in tissue engineering. Our lab focuses on strategies that promote the formation of microvascular networks essential for proper oxygen transport and nutrient supply to the core of the constructs. Specifically, we develop microfabrication techniques to generate 3D vascularized tissues within custom made perfusion systems and to study the interactions between human endothelial cells, human mesenchymal stem cells and tissue specific cells within biomimetic hydrogels. We also employ statistical experimental methods to identify the optimal combination of experimental parameters (e.g. cell density, cell ratio, matrix composition) to generate interconnected capillary networks within engineered tissues.


NEWS / EVENTS

15/05/2010 Meet us at the Lab-on-a-Chip European Congress in Dublin (25-26 May)!
31/03/2009 Dr. Matteo Moretti wins the Prize “Ricerca.tissimi”
We are proud to announce that CTE-Lab PI Matteo Moretti, PhD, has been awarded with the Prize “Ricerca.tissimi” to the 20 Best International Achievements within Health, Environmental and Industrial Pr

Pages