Vascularization strategies

The generation of thick, vascularized three-dimensional (3D) tissues is a key challenge in tissue engineering. Our lab focuses on strategies that promote the formation of microvascular networks essential for proper oxygen transport and nutrient supply to the core of the constructs. Specifically, we develop microfabrication techniques to generate 3D vascularized tissues within custom made perfusion systems and to study the interactions between human endothelial cells, human mesenchymal stem cells and tissue specific cells within biomimetic hydrogels. We also employ statistical experimental methods to identify the optimal combination of experimental parameters (e.g. cell density, cell ratio, matrix composition) to generate interconnected capillary networks within engineered tissues.


15/12/2010 Silvia Lopa starts her PhD!!!
We are happy to announce that Silvia Lopa will soon start her PhD in Biotechnology Applied to Medical Science (University of Milan) as part of our research group!
03/11/2010 Meet us at TeRM in Lattrop (18-19 Nov)!
01/09/2010 Meet us at TERMIS-AP in Sidney (15-17 Sep)!
01/06/2010 Meet us at TERMIS-EU 2010 in Galway (13-17 Jun)!
18/05/2010 Dr. Matteo Moretti wins the NASA Tech Brief Award
We are happy to announce that CTE-Lab PI Matteo Moretti, PhD, has been awarded with the NASA Tech Brief Award for the development of scientific and technical innovations