Biofabrication

Biofabrication can be defined as the production of complex living and non-living biological products from raw materials such as living cells, molecules, extracellular matrices, and biomaterials. Our lab exploits biofabrication strategies for the generation of vascularized constructs and for scaffold prototyping. We biofabricated perfusable vascular-like structures through the electrochemical transfer of endothelial cells to fibrin hydrogel, resulting in the formation of endothelial cell-lined vessels. We also applied photo-mold patterning to fabricate 3D cell laden hydrogel micro-patterns embedded in microfluidic devices. Furthermore, we exploited low-cost rapid prototyping techniques to generate implantable multi-well fibrin scaffold to study the influence of cell distribution on cell differentiation and the interaction between multiple cell types within a 3D environment.


NEWS / EVENTS

20/08/2011 Meet us at EORS 2011 in Vienna (1-2 Sep)!
03/06/2011 Meet us at TERMIS-EU 2011 in Granada (7-10 Jun)!
22/02/2011 Best Paper for the 2011 Draper Technology Digest
We are happy to announce that the paper “In vitro generation of mechanically functional cartilage grafts based on adult human stem cells and 3D-woven poly(epsilon-caprolactone) scaffolds” (Biomaterial
21/04/2011 OPB selected for Italia150 Exhibition
We are proud to announce that the Oscillating Perfusion Bioreactor patented by Matteo Moretti, PhD, has been selected from WIRED magazine for “Italy’s best 150 projects representing the future” at the
02/01/2011 Meet us at ORS 2011 in Long Beach (13-16 Jan)!

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